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| Checkpoint : Nucleotide Excision Repair | ||||||||||
| S. cerevisiae | S. pombe | Human | Mw(kD) | Chromosome | Structure or Function | Description | ||||
| Rad10 | ERCC1 | 31 | endnuclease | |||||||
| Rad3 | XPD/ERCC2 | 87 | 5'-3' helicase, TFIIH subunit | |||||||
| Rad25 (Ssl2) | XPB/ERCC3 | 89 | 3'-5' helicase, TFIIH subunit | |||||||
| Rad1 | rad16 | XPF/ERCC4 | 104 | 16p13.1-13.2 | NER, 5'-nicking enzyme | |||||
| Rad2 | XPG/ERCC5 | 133 | endnuclease, 3'-nicking enzyme | |||||||
| Rad14 | XPA | 31 | Zn finger | |||||||
| Rad4 | XPC | 106 | SSB | |||||||
| Rad23B | HHR23B | 43 | ubiquitin like motif | |||||||
| Tfb1 | p62 | 62 | TFIIH subunit | |||||||
| Tfb2 | p50 | 50 | TFIIH subunit, WD40-repeat | |||||||
| Ssl1 | p44 | 44 | TFIIH subunit, Zn finger | |||||||
| Tfb1 | p34 | 34 | TFIIH subunit, Zn finger | |||||||
| Rfa1 | RPAp70 | 68 | SSB | |||||||
| Rfa2 | RPAp34 | 29 | SSB | |||||||
| Rfa3 | RPAp11 | 14 | SSB | |||||||
| DDBp127 | 127 | damaged DNA binding protein | ||||||||
| DDBp41 | 48 | XPE? | ||||||||
| Rad26 | CSB/ERCC6 | 168 | TCR, DNA helicase motif | |||||||
| Rad28 | CSA/ERCC8 | 44 | TCR, WD-repeat | |||||||
| Pol30 | PCNA | 34 | DNA pol delta accessory protein | movable clamp | ||||||
| Cdc44 | hRFC140 | 128 | DNA dependent ATPase complex | component of clamp loader complex | ||||||
| ScRfc4 | hRFC40 | 39 | DNA dependent ATPase complex | component of clamp loader complex | ||||||
| ScRfc5 | hRFC38 | 41 | DNA dependent ATPase complex | component of clamp loader complex | ||||||
| ScRfc2 | hRFC37 | 40 | DNA dependent ATPase complex | component of clamp loader complex | ||||||
| ScRfc3 | hRFC36 | 39 | DNA dependent ATPase complex | component of clamp loader complex | ||||||
| Cdc9 | DNA ligase I | 102 | DNA ligase | DNA ligase | ||||||