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| DNA Replication : DNA polymerase | |||||||||||
| S. cerevisiae | Mw (kDa) | S. pombe | Human | Mw (kDa) | Chromosome | Description | |||||
| POL1/CDC17 | 180 | essential | DNA pol alpha catalytic subunit | 185 | DNA replication, lagging strand | ||||||
| POL12 | 86 | essential | accessory protein | 68 | |||||||
| PRI2 | 58 | essential | accessory protein | 54 | 6p11.1-12 | ||||||
| PRI1 | 48 | essential | DNA primase | 46 | 12q13.3 | DNA primase | |||||
| POL2 | 256 | essential | DNA pol epsilon catalytic subunit | 225 | 12q24.3 | DNA replication, leading strand, DNA repair, 3'-5' exonuclease | |||||
| DPB2 | 80 | essential | accessory protein | 14q21-22 | |||||||
| DPB3 | 34 | non-essential | accessory protein | ||||||||
| DPB3 | 31 | non-essential | accessory protein | ||||||||
| DPB4 | 29 | ? | . | ||||||||
| POL3/CDC2 | 125 | essential | DNA pol delta catalytic subunit | 125 | 19q13.3-13.4 | DNA replication, leading strand, DNA repair, 3'-5' exonuclease | |||||
| HYS2 | 56 | ? | accessory protein | 7 | |||||||
| POL4 | 68 | essential | DNA pol beta | 39 | 8p11-12 | DNA repair, recombination | |||||
| MIP1 | 144 | DNA pol gamma | mitochondrial DNA replication, 3'-5' exonuclease | ||||||||
| REV3 | 173 | DNA pol zeta/Rev3-Rev7Hs | 6q22 | UV-damaged DNA repair | |||||||
| REV7 | 29 | . | 39 | DNA repair, recombination | |||||||
| POL5 | 116 | DNA pol eta/hRad30A | XPV responsible gene | ||||||||
| DNA pol theta | 3q13.31 | similar to Drosophila mus308 and C. elegance mus1 | |||||||||
| DNA pol iota/hRad30B | 18q21.1 | similar to pol eta (hRad30A) | |||||||||
| DNA pol kappa | |||||||||||
| DNA pol lambda/DNA pol beta-N | involed in meiosis | ||||||||||
| DNA pol mu/TdT-N | 7p13 | similar to TdT, act as DNA mutator. | |||||||||
| human DINB1 | 5q13 | UmuC/DinB(DNA pol IV) superfamily | |||||||||
| human Rev1 | 2q11.1-11.2 | template dependent deoxycytidyl transferase | |||||||||
| AF044578 | 4p16.3 | family A polymerase | |||||||||
| - | TdT | involved in TCR gene re-arrangement | |||||||||