|
|||||||||
| CDCs : S. pombe | |||||||||
| S. pombe | S. cerevisiae | Human | Drosophila | Description | |||||
| cdc1 | HYS2 | DNA pol delta small subunit | DNA pol delta small subunit | ||||||
| cdc2 | cdc28 | cdc2Hs/cdk1 | protein kinase | ||||||
| cdc3 | prophilin (actin-binding protein), essential for cytokinesis | ||||||||
| cdc5 | c-Myb? | c-Myb like transcription factor | |||||||
| cdc6/DNA pol III | DNA pol delta catalytic subunit | DNA pol delta catalytic subunit | |||||||
| cdc7 | protein kinase, genetic interaction with cdc11, cdc14 and cdc16 | ||||||||
| cdc8 | topolomyosine | ||||||||
| cdc10 | Swi6 | transcription factor, forming Res1/Cdc10, Res2/Cdc10/Rep2 and Res2/Cdc10/Rep1 | |||||||
| cdc11 | |||||||||
| cdc12 | BNI1 | prophilin interacting protein, required for cytokinesis, component of cell division ring | |||||||
| cdc13 | cyclinB | B-type cyclin | |||||||
| cdc14 | required for septum formation | ||||||||
| cdc15 | key element in the reorgarnization of F-actin, contains coiled-colil at N-ter, SH3 domain | ||||||||
| cdc16 | Bub2 | GAP | |||||||
| cdc17 | CDC9 | DNA ligase I | DNA ligase | ||||||
| cdc18 | CDC6 | CDC6Hs | involved in initiation of DNA replication | ||||||
| cdc19/nda1 | MCM2 | MCM2/BG28 | DmMCM2 | ||||||
| cdc20 | POL2 | DNA pol epsilon catalytic subunit | DNA polymerase epsilon | ||||||
| cdc21 | CDC54 | MCM4 | |||||||
| cdc22 | ribonucleotide reductase | ||||||||
| cdc23 | MCM10/DNA43 | - | - | ||||||
| cdc24 | required for chromosome integrity, genetically interact with RFC and PCNA | ||||||||
| cdc25 | cdc25A, B, C | tyrosil protein phophatase | |||||||
| cdc27 | required for the G2-M transition | ||||||||
| cdc28 | RNA dependent ATPase/helicase | ||||||||