Product Literature
CycLex Deacetylase Kit's Measurement Principle
Product Reference
CY-1160 CycLex Rho-kinase Assay Kit
- (1) PMID: 15184877
Miyoshi K, Wakioka T, Nishinakamura H, Kamio M, Yang L, Inoue M, Hasegawa M, Yonemitsu Y, Komiya S, Yoshimura A.
The Sprouty-related protein, Spred, inhibits cell motility, metastasis, and Rho-mediated actin reorganization.
Oncogene. 2004 Jul 22;23(33):5567-76.
- (2) PMID: 15337751
Toda M, Dawson M, Nakamura T, Munro PM, Richardson RM, Bailly M, Ono SJ.
Impact of engagement of FcepsilonRI and CC chemokine receptor 1 on mast cell activation and motility.
J Biol Chem. 2004 Nov 12;279(46):48443-8.
- (3) PMID: 15705589
Madonna R, Di Napoli P, Massaro M, Grilli A, Felaco M, De Caterina A, Tang D, De Caterina R, Geng YJ.
Simvastatin attenuates expression of cytokine-inducible nitric-oxide synthase in embryonic cardiac myoblasts.
J Biol Chem. 2005 Apr 8;280(14):13503-11.
- (4) PMID: 16204049
Salhia B, Rutten F, Nakada M, Beaudry C, Berens M, Kwan A, Rutka JT.
Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1.
Cancer Res. 2005 Oct 1;65(19):8792-800.
- (5) PMID: 16720831
Sapet C, Simoncini S, Loriod B, Puthier D, Sampol J, Nguyen C, Dignat-George F, Anfosso F.
Thrombin-induced endothelial microparticle generation: identification of a novel pathway involving ROCK-II activation by caspase-2.
Blood. 2006 Sep 15;108(6):1868-76.
- (6) PMID: 16450390
Riganti C, Orecchia S, Pescarmona G, Betta PG, Ghigo D, Bosia A.
Statins revert doxorubicin resistance via nitric oxide in malignant mesothelioma.
Int J Cancer. 2006 Jul 1;119(1):17-27.
- (7) PMID: 15555614
Galaria II, Fegley AJ, Nicholl SM, Roztocil E, Davies MG.
Differential regulation of ERK1/2 and p38(MAPK) by components of the Rho signaling pathway during sphingosine-1-phosphate-induced smooth muscle cell migration.
J Surg Res. 2004 Dec;122(2):173-9.
- (8) PMID: 17005937
Fu P, Liu F, Su S, Wang W, Huang XR, Entman ML, Schwartz RJ, Wei L, Lan HY.
Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice.
J Am Soc Nephrol. 2006 Nov;17(11):3105-14.
- (9) PMID: 17145782
Katiyar S, Jiao X, Wagner E, Lisanti MP, Pestell RG.
Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.
Mol Cell Biol. 2007 Feb;27(4):1356-69.
CY-1161 CycLex cyclic GMP dependent protein kinase (cGK) Assay Kit
- (1) PMID: 15576651
Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA.
cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism.
Circ Res. 2005 Jan 7;96(1):100-9.
- (2) PMID: 15665834
Takimoto E, Champion HC, Li M, Belardi D, Ren S, Rodriguez ER, Bedja D, Gabrielson KL, Wang Y, Kass DA.
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy.
Nat Med. 2005 Feb;11(2):214-22.
- (3) PMID: 16855220
Lee JH, Ragolia L.
AKT phosphorylation is essential for insulin-induced relaxation of rat vascular smooth muscle cells.
Am J Physiol Cell Physiol. 2006 Dec;291(6):C1355-65.
- (4) PMID: 17158223
Hsu LL, Champion HC, Campbell-Lee SA, Bivalacqua TJ, Manci EA, Diwan BA, Schimel DM, Cochard AE, Wang X, Schechter AN, Noguchi CT, Gladwin MT.
Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability.
Blood. 2006 Dec 7; [Epub ahead of print]
CY-1163 CycLex Polo-like kinase 1 Assay/Inhibitor Screening Kit
- (1) PMID: 15664519
Liu Y, Shreder KR, Gai W, Corral S, Ferris DK, Rosenblum JS.
Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase.
Chem Biol. 2005 Jan;12(1):99-107.
CY-1165 CycLex Aurora A Kinase Assay/Inhibitor Screening Kit
- (1)
Adrianne E. Hontz, Sara A. Li, Jeffrey L. Salisbury, Wilma L. Lingle, and Jonathan J. Li
CARCINOGENESIS 10: GENOMIC INSTABILITY: Enrichment of amplified centrosomes and Aurora A and B from solely estrogen-induced ectopic uterine stem cell tumors (EUTK) in the Syrian hamster kidney.
AACR Meeting Abstracts, Apr: 1326, 2006.
CY-1150 CycLex HDACs Deacetylase Fluorometric Assay Kit
- (1) PMID: 15927959
Gray SG, Iglesias AH, Lizcano F, Villanueva R, Camelo S, Jingu H, Teh BT, Koibuchi N, Chin WW, Kokkotou E, Dangond F.
Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein.
J Biol Chem. 2005 Aug 5;280(31):28507-18.
- (2) PMID: 16818655
Inoue S, Mai A, Dyer MJ, Cohen GM.
Inhibition of histone deacetylase class I but not class II is critical for the sensitization of leukemic cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.
Cancer Res. 2006 Jul 1;66(13):6785-92.
CY-1151 CycLex SIRT1/SIR2 Fluorometric Deacetylase Assay kit
- (1) PMID: 15673775
Sereno D, Alegre AM, Silvestre R, Vergnes B, Ouaissi A.
In vitro antileishmanial activity of nicotinamide.
Antimicrob Agents Chemother. 2005 Feb;49(2):808-12.
Antibody
- (1) PMID: 15867347
CY-M1020 Anti-Phospho-Lats2 Ser83 Clone ST-3B11
Kimura MT, Mori T, Conroy J, Nowak NJ, Satomi S, Tamai K, Nagase H.
Two functional coding single nucleotide polymorphisms in STK15 (Aurora-A) coordinately increase esophageal cancer risk.
Cancer Res. 2005 May 1;65(9):3548-54.
- (2) PMID: 15147269
CY-M1030 Anti-Human Lats2 Clone ST-3D10
Toji S, Yabuta N, Hosomi T, Nishihara S, Kobayashi T, Suzuki S, Tamai K, Nojima H.
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
Genes Cells. 2004 May;9(5):383-97.
- (3) PMID: 16818655
CY-P1011 Anti-HDAC1 and/or CY-P1012 Anti-HDAC2
Inoue S, Mai A, Dyer MJ, Cohen GM.
Inhibition of histone deacetylase class I but not class II is critical for the sensitization of leukemic cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.
Cancer Res. 2006 Jul 1;66(13):6785-92.